As the story begins, the scene is set on a lovely, albeit eccentric cruise ship. The decoration and design seems to be equally inspired by classic Greek and modern Umbrella Corp. The aesthetics of the ship are quite pleasing, but the camera angles are, at times, a bit too "Resident Evil" for my tastes; you're in a bad angle and that's the only angle you get. Mind you, a lot of the area is free roaming with a controllable camera, but the camera controls take a bit of getting used to.
One very interesting aspect of Death By Degrees is the X-ray attack view mode that the game slips in to when a critical strike is being made. This occurs in some cut scenes, but is also an attack type that can be performed when your focus is built up. The camera changes to an X-ray view and you can target your enemy's vital organs; build up this critical strike skill and you'll be able to make multiple attacks in the same critical strike attack.
Poor Nina tends to work her way through her outfits; first totally ruining her beautiful evening gown in her on-deck fights, then when she finds a replacement, slowly wearing that down. It's a nice touch of realism and and interesting bit of gratuitous eye-candy at the same time.
The music in Death By Degrees plays a helpful, if not vital, role; the music plays when bad stuff is about to happen. Specifically, if you can hear music playing, someone knows you're there. When you're in a fight, listen for the music to stop before you assume that the enemies are all gone.